Sen. Edward M. Kennedy says he has a malignant brain tumor. Doctors for the Massachusetts Democrat say it was discovered after a seizure this weekend.

Barack Obama will reach for a symbolic tipping point in the Oregon and Kentucky primaries Tuesday — a majority of pledged delegates offered in the Democratic presidential contest.

The Senate Tuesday kicked off debate on legislation to add a grab bag of domestic programs to President Bush's war request, including work permits for immigrant farm labor and heating subsidies for the poor. The White House renewed its veto threat.

National polls show presumptive GOP nominee John McCain narrowly trailing Barack Obama and Hillary Clinton, often by only 2 to 3 points.

It can still be a victory lap even if you don't win. Hillary Clinton should be thinking about her legacy, and how best to use it. Anna Quindlen explains.

The messy process of trying to purge John McCain’s campaign of conflicts of interest has so far focused only more attention on the backgrounds of his advisers.

Republican presidential candidate John McCain marked Cuban Independence Day on Tuesday with a fresh slap at Barack Obama for a pledge to meet Cuba's leader if elected in November.

President Bush has apologized to Iraqi Prime Minister Nuri al-Maliki and promised prosecution of a U.S. soldier accused of using a copy of the Quran for target practice, Iraq said on Tuesday.

New York Gov. David Paterson has been diagnosed with acute glaucoma, aides said Tuesday after he was taken to a hospital in Manhattan with migraine-like symptoms.

The White House on Monday called on NBC News to set the record straight on "deceitful" editing of an interview with President Bush, in which correspondent Richard Engel asks whether comments about the president of Iran were directed at Barack Obama.

The Bush administration is defending its decision to push food-based biofuels as food costs rise at home and abroad, saying the renewable fuels are only a small part of the problem.

President Bush will help Republican John McCain raise money later this month in Arizona. Beyond that, the White House isn't saying how much the two will campaign together.

To confront the Obama juggernaut, Senator John McCain, whose fund-raising has badly trailed that of his Democratic counterparts, is leaning on the Republican National Committee.

Republican John McCain accused Democrat Barack Obama of inexperience and reckless judgment for saying Iran does not pose the same serious threat to the United States as the Soviet Union did in its day.

Democrat Hillary Rodham Clinton on Monday said her opponent Barack Obama may be getting a little ahead of himself in acting like the party's nominee before the final contests of the primary season are over.

President Bush, acknowledging the economic "tough times" for many Americans, said Monday that he remains opposed to any homeowner rescue legislation that would be a bailout for lenders.

John McCain plans to continue, and perhaps even accelerate, George W. Bush’s conservative counter-revolution at the Supreme Court.

Democrat Barack Obama has a message for Tennessee's Republican Party: "Lay off my wife."

Democrat Barack Obama was greeted by the biggest crowd of his campaign: 65,000 who packed into a riverside park in Portland, Ore. Fire officials said 15,000 more were left outside.

Both candidates are campaigning hard to win the support of the female voters who backed Hillary Clinton.